HDI Publications by date

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Real-world evidence for patient outcomes and mutational burden in non-small cell lung (NSCLC) cancer patients in England using EGFR biomarker test data from routine clinical care

Hagenaars S, Ingleby FC, Lambova A, Gaultney J, Parimi M, Huynh J, Benson S, Muwaffak M, Jose S, Frayling L, Lascano V. Download PDF version of the poster …

Real-world outcomes and biomarker testing in cancer patients: exploration of a novel genetic database from routine clinical practice in England

Fiona C Ingleby, IQVIA, London, UK Saskia P Hagenaars, IQVIA, London, UK Alexandrina Lambova, IQVIA, Sofia, Bulgaria Mounika Parimi, IQVIA, London, UK Stephen Benson, IQVIA, London, UK, Sophie Jose, HDI, London, …

First-line treatment patterns and overall survival of patients with advanced Merkel cell carcinoma in England from 2013-2022: Results of a nationwide observational cohort study

C. Knott, S. Mahmoudpour, M. Kearney, E. Boutmy, P. Verpillat. First-line treatment (tx) patterns and overall survival (OS) of patients (pts) with advanced Merkel cell carcinoma (aMCC) in England from …

First-line treatment patterns and overall survival of patients with advanced Merkel cell carcinoma in England from 2013-2022: results of a nationwide observational cohort study

Knott CS, Mahmoudpour SH, Kearney M, Boutmy E, Verpillat P. First-line treatment patterns and overall survival of patients with advanced Merkel cell carcinoma in England from 2013-2022: results of a nationwide …

Evidence into practice: a national cohort study of NICE-recommended oncological drug therapy utilisation among women diagnosed with invasive breast cancer in England

Gannon MR, Dodwell D, Aggarwal A, Park MH, Miller K, Horgan K, et al. Br J Cancer 2023. Abstract: Background Multiple drug treatments are approved for invasive breast cancer (IBC). We investigated uptake of …

P47 Treatment pathways of patients diagnosed with hepatocellular carcinoma (HCC) after initial locoregional treatment in England

Amy Zalin-Miller, Sophie Jose, Sophia Le Mare, Betina Blak T https://gut.bmj.com/content/72/Suppl_3/A42.2 Background Hepatocellular carcinoma (HCC) early-stage treatment options include potentially curative …

Estimating surgery, radiotherapy and systemic anti-cancer therapy treatment costs for cancer patients by stage at diagnosis

Wills, L., Nagarwalla, D., Pearson, C. et al. Abstract: The increasing burden of cancer has economic implications for the healthcare system in England. However, there is limited evidence on the cost of cancer …

Treatments into Routine Clinical Practice for the Treatment of Patients with Advanced or Metastatic Cancers

Mahmoudpour SH, Knott CS, Amin A, Boutmy E, Verpillat P. Integration of Immuno-oncology (IO) Treatments into Routine Clinical Practice for the Treatment of Patients with Advanced or Metastatic Cancers: Analysis …

Outcomes of dostarlimab versus chemotherapy in post-platinum patients with recurrent/advanced endometrial cancer

Goulden S, Heffernan K, Sen Nikitas F, et al. Outcomes of dostarlimab versus chemotherapy in post-platinum patients with recurrent/advanced endometrial cancer: data from the GARNET trial and the National Cancer …

Completeness of endocrine therapy information in the Primary Care Prescription Database (PCPD) and secondary care treatment datasets: A national population-based cohort study using routine healthcare data

Gannon MR, Dodwell D, Miller K, Horgan K, Clements K, Medina J, et al. Abstract Background Endocrine therapy (ET) is a widely used treatment for breast cancer. In the UK, use is typically initiated in secondary …

Regional variation in routes to diagnosis of cholangiocarcinoma in England from 2006 to 2017

Zalin-Miller A, Jose S, Knott C, Paley L, Tataru D, Morement H, Toledano MB, Khan SA. Abstract: Background: Incidence of cholangiocarcinoma (CCA) is rising, with overall prognosis re-maining very poor. Reasons …

Variation in Rates of Post-Mastectomy Radiotherapy Among Women with Early Invasive Breast Cancer in England and Wales: A Population-Based Cohort Study.

Miller K, Gannon MR, Medina J, Clements K, Dodwell D, Horgan K, et al. Abstract: Aims This study examined whether patterns of post-mastectomy radiotherapy (PMRT) among women with early invasive breast cancer …
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